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Reversibly and selectively blocks Tie2 kinase activity (IC50 = 250 nM); reduces angiogenesis in a Matrigel neovascularization assay and delays tumor growth in MOPC-315 plasmacytoma and SVR angiosarcoma xenograft models
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
HR2-910-12/Crystal Screen #12 (A12), 185 ml - 0.2 M Magnesium chloride hexahydrate, 0.1 M HEPES sodium pH 7.5, 30% v/v 2-Propanol. Please note items from this supplier are non-returnable.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
HR2-910-13/Crystal Screen #13 (B1), 185 ml - 0.2 M Sodium citrate tribasic dihydrate, 0.1 M TRIS hydrochloride pH 8.5, 30% v/v Polyethylene glycol 400. Please note items from this supplier are non-returnable.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
An inhibitor of GLS1 (IC50 = 0.021 μM); inhibits the growth of NCI H1703 NSCLC cells in vitro (GI50 = 0.011 μM); reduces tumor growth, increases tumor levels of glutamine, and decreases tumor levels of glutamate and aspartate in an NCI H1703 mouse xenograft model at 100 mg/kg
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion homing receptors The encoded protein contains a C-type lectin-like domain a calcium-binding epidermal growth factor-like domain and two short complement-like repeats The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells facilitating their migration into secondary lymphoid organs and inflammation sites Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy Alternatively spliced transcript variants have been found for this gene
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Mammalian sEH is a member of the α/β-hydrolase fold family of enzymes that catalyze the hydrolysis of exogenous and endogenous epoxides to vicinal diols. Endogenous substrates for sEH include EETs which exhibit vasodilatory and anti-inflammatory activity. Cayman’s sEH Cell-Based Assay provides a convenient 96-well plate, fluorescence-based method for detecting epoxide hydrolase activity in whole cells. The assay utilizes Epoxy Fluor 7, a sensitive fluorescent substrate for sEH that can be used to monitor the activity of both human and murine enzymes.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More